BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
NSMF
Jac, Jacob, Nelf
NMDA receptor synaptonuclear signaling and neuronal migration factor
GO Process (8)
GO Function (2)
GO Component (15)
Gene Ontology Biological Process
- cellular response to amino acid stimulus [IDA]
- cellular response to electrical stimulus [IDA]
- cellular response to gonadotropin stimulus [ISO, ISS]
- positive regulation of neuron migration [ISO, ISS]
- positive regulation of protein dephosphorylation [IMP]
- regulation of dendrite morphogenesis [IMP]
- regulation of neuron apoptotic process [IMP]
- regulation of neuronal synaptic plasticity [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical dendrite [IDA]
- cortical cytoskeleton [IDA]
- cytoplasm [ISO, ISS]
- dendrite [IDA]
- membrane [IDA]
- neuron projection [IDA]
- nuclear envelope [IDA]
- nuclear euchromatin [IDA]
- nuclear matrix [IDA]
- nuclear membrane [IDA]
- nucleoplasm [ISO]
- nucleus [IDA, ISO, ISS]
- perikaryon [IDA]
- postsynaptic density [IDA]
- synapse [IDA]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID