BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
ATP2B2
PMCA2
ATPase, Ca++ transporting, plasma membrane 2
GO Process (33)
GO Function (9)
GO Component (12)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- auditory receptor cell stereocilium organization [ISO]
- brain development [IEP]
- cGMP metabolic process [ISO]
- calcium ion export [IMP]
- calcium ion transmembrane transport [ISO, ISS]
- calcium ion transport [ISO]
- cell morphogenesis [ISO]
- cellular calcium ion homeostasis [ISO]
- cerebellar Purkinje cell differentiation [ISO]
- cerebellar Purkinje cell layer morphogenesis [ISO]
- cerebellar granule cell differentiation [ISO]
- cerebellum development [ISO]
- cochlea development [ISO]
- cytosolic calcium ion homeostasis [ISO]
- detection of mechanical stimulus involved in sensory perception of sound [ISO]
- inner ear development [ISO]
- inner ear morphogenesis [ISO]
- inner ear receptor cell differentiation [ISO]
- lactation [ISO]
- locomotion [ISO]
- locomotory behavior [ISO]
- neural retina development [IEP]
- neuromuscular process controlling balance [ISO]
- neuron differentiation [ISO, ISS]
- organelle organization [ISO]
- otolith mineralization [ISO]
- positive regulation of calcium ion transport [ISO]
- regulation of cell size [ISO]
- regulation of synaptic plasticity [ISO]
- sensory perception of sound [ISO, ISS]
- serotonin metabolic process [ISO]
- synapse organization [ISO]
Gene Ontology Molecular Function- ATP binding [IDA, ISO, ISS]
- PDZ domain binding [IPI, ISO, ISS]
- acetylcholine receptor binding [IDA]
- calcium ion binding [ISO, ISS]
- calcium-dependent ATPase activity [ISO]
- calcium-transporting ATPase activity [IDA, IMP, ISO, ISS, TAS]
- calmodulin binding [ISO, ISS]
- glutamate receptor binding [IPI]
- protein C-terminus binding [ISO, ISS]
- ATP binding [IDA, ISO, ISS]
- PDZ domain binding [IPI, ISO, ISS]
- acetylcholine receptor binding [IDA]
- calcium ion binding [ISO, ISS]
- calcium-dependent ATPase activity [ISO]
- calcium-transporting ATPase activity [IDA, IMP, ISO, ISS, TAS]
- calmodulin binding [ISO, ISS]
- glutamate receptor binding [IPI]
- protein C-terminus binding [ISO, ISS]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID