BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PFN1
profilin 1
GO Process (16)
GO Function (8)
GO Component (8)
Gene Ontology Biological Process
- actin polymerization or depolymerization [TAS]
- cellular response to growth factor stimulus [IEP]
- negative regulation of actin filament bundle assembly [ISO]
- negative regulation of actin filament polymerization [ISO]
- negative regulation of stress fiber assembly [ISO]
- neural tube closure [ISO]
- positive regulation of ATPase activity [ISO]
- positive regulation of DNA metabolic process [IDA]
- positive regulation of actin filament polymerization [ISO]
- positive regulation of epithelial cell migration [ISO]
- positive regulation of ruffle assembly [ISO]
- positive regulation of stress fiber assembly [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of viral transcription [IMP]
- regulation of transcription from RNA polymerase II promoter [ISO]
- response to organic substance [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID