BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PHB
prohibitin
GO Process (24)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- DNA biosynthetic process [ISO]
- cellular response to interleukin-6 [ISO]
- histone deacetylation [ISO]
- negative regulation of androgen receptor signaling pathway [ISO]
- negative regulation of apoptotic process [IMP]
- negative regulation of cell growth [ISO]
- negative regulation of cell proliferation [IMP, ISO]
- negative regulation of glucocorticoid receptor signaling pathway [ISO]
- negative regulation of transcription by competitive promoter binding [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- negative regulation of transcription, DNA-templated [ISO]
- organ regeneration [IEP]
- osteoblast differentiation [ISO]
- ovarian follicle atresia [IEP]
- ovarian follicle development [IEP]
- positive regulation of transcription, DNA-templated [ISO]
- progesterone receptor signaling pathway [ISO]
- regulation of transcription, DNA-templated [ISO]
- response to cytokine [IEP]
- response to drug [IEP]
- response to ethanol [IEP]
- response to immobilization stress [IEP]
- response to peptide hormone [IEP]
- transcription from RNA polymerase II promoter [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cytoplasm [IDA, ISO]
- extracellular vesicular exosome [ISO]
- extrinsic component of mitochondrial outer membrane [IDA]
- integral component of plasma membrane [ISO]
- membrane [ISO]
- mitochondrial crista [IDA]
- mitochondrial inner membrane [ISO]
- mitochondrion [IDA, ISO]
- myelin sheath [ISO]
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID