BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
RAB14
RAB14, member RAS oncogene family
GO Process (12)
GO Function (6)
GO Component (23)
Gene Ontology Biological Process
- GTP catabolic process [IBA, ISO]
- Golgi to endosome transport [ISO, ISS, TAS]
- Rab protein signal transduction [IBA]
- apical protein localization [IDA]
- body fluid secretion [IMP]
- endocytic recycling [ISO, ISS]
- fibroblast growth factor receptor signaling pathway [ISO, ISS]
- intracellular protein transport [IBA]
- intracellular transport [NAS]
- phagolysosome assembly involved in apoptotic cell clearance [IBA]
- regulation of protein localization [IDA, IMP, ISO]
- vesicle-mediated transport [NAS]
Gene Ontology Molecular Function- GDP binding [IBA, ISO, ISS]
- GTP binding [IBA, ISO, ISS]
- GTPase activity [IBA, ISO, ISS, NAS]
- glycoprotein binding [IDA]
- myosin V binding [ISO]
- protein binding [IPI]
- GDP binding [IBA, ISO, ISS]
- GTP binding [IBA, ISO, ISS]
- GTPase activity [IBA, ISO, ISS, NAS]
- glycoprotein binding [IDA]
- myosin V binding [ISO]
- protein binding [IPI]
Gene Ontology Cellular Component
- Golgi stack [IDA]
- alveolar lamellar body [IDA]
- apical plasma membrane [IDA]
- cell [ISO]
- cytoplasm [ISO]
- cytoplasmic vesicle membrane [TAS]
- cytosol [IDA]
- early endosome [IDA]
- extracellular vesicular exosome [ISO]
- intracellular [ISO]
- intracellular membrane-bounded organelle [ISO]
- late endosome [IDA]
- lysosomal membrane [ISO]
- lysosome [IDA]
- nuclear outer membrane-endoplasmic reticulum membrane network [IDA]
- perinuclear region of cytoplasm [IDA]
- phagocytic vesicle [IBA, ISO, ISS]
- plasma membrane [IDA]
- primary cilium [ISO]
- recycling endosome [ISO, ISS]
- rough endoplasmic reticulum [IDA]
- trans-Golgi network transport vesicle [IDA]
- transport vesicle [IDA]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID