BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
RAB3A
RAB3
RAB3A, member RAS oncogene family
GO Process (23)
GO Function (9)
GO Component (13)
Gene Ontology Biological Process
- GTP catabolic process [IBA, ISO]
- Rab protein signal transduction [IBA, IC]
- axonogenesis [ISO]
- intracellular protein transport [IBA]
- lung development [ISO]
- maintenance of presynaptic active zone structure [ISO]
- mitochondrion organization [ISO]
- neuromuscular synaptic transmission [ISO]
- positive regulation of ATPase activity [IDA]
- positive regulation of regulated secretory pathway [ISO]
- post-embryonic development [ISO]
- protein localization to plasma membrane [IBA]
- protein secretion [IBA]
- regulation of exocytosis [IBA, ISO]
- regulation of short-term neuronal synaptic plasticity [ISS]
- regulation of synaptic vesicle fusion to presynaptic membrane [ISO, ISS]
- respiratory system process [ISO]
- response to electrical stimulus [ISO]
- sensory perception of touch [ISO]
- synaptic vesicle exocytosis [IMP, ISO]
- synaptic vesicle maturation [ISO]
- synaptic vesicle recycling [IMP]
- vesicle docking involved in exocytosis [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID