BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
GO Process (9)
GO Function (5)
GO Component (14)
Gene Ontology Biological Process
- branching morphogenesis of an epithelial tube [ISO]
- circadian regulation of gene expression [ISO, ISS]
- entrainment of circadian clock by photoperiod [ISO, ISS]
- lung development [ISO]
- positive regulation of extrinsic apoptotic signaling pathway in absence of ligand [ISO]
- protein dephosphorylation [IDA, ISO]
- regulation of circadian rhythm [ISO, ISS]
- regulation of glycogen biosynthetic process [IDA]
- regulation of glycogen catabolic process [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- MLL5-L complex [ISO]
- PTW/PP1 phosphatase complex [ISO, ISS]
- cytoplasm [IDA, ISO]
- cytosol [TAS]
- dendritic spine [IDA]
- extracellular vesicular exosome [ISO]
- glycogen granule [IDA]
- neuron projection [IDA]
- neuronal cell body [IDA]
- nucleoplasm [ISO]
- nucleus [IDA, ISO]
- perikaryon [IDA]
- plasma membrane [ISO]
- protein phosphatase type 1 complex [IDA]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID