BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
ATP1B1
ATPBS
ATPase, Na+/K+ transporting, beta 1 polypeptide
GO Process (25)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- blastocyst development [ISO]
- cardiac muscle contraction [ISO]
- cellular calcium ion homeostasis [ISO]
- cellular potassium ion homeostasis [ISO]
- cellular sodium ion homeostasis [ISO]
- membrane repolarization [ISO]
- metal ion transport [IDA]
- positive regulation of ATP catabolic process [ISO]
- positive regulation of ATPase activity [ISO]
- positive regulation of calcium:sodium antiporter activity [ISO]
- positive regulation of potassium ion import [ISO]
- positive regulation of potassium ion transmembrane transporter activity [ISO]
- positive regulation of sodium ion export from cell [ISO]
- potassium ion import [ISO]
- potassium ion transport [IDA]
- protein localization to plasma membrane [ISO]
- protein stabilization [ISO]
- regulation of calcium ion transmembrane transport [ISO]
- regulation of cardiac muscle contraction by calcium ion signaling [ISO]
- regulation of gene expression [ISO]
- relaxation of cardiac muscle [ISO]
- response to hypoxia [IDA]
- sodium ion export from cell [ISO]
- sodium ion transmembrane transport [IDA]
- sodium ion transport [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID