BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
STOML2
stomatin (Epb7.2)-like 2
GO Process (15)
GO Function (1)
GO Component (11)
Gene Ontology Biological Process
- CD4-positive, alpha-beta T cell activation [ISO, ISS]
- T cell receptor signaling pathway [ISO, ISS]
- cellular calcium ion homeostasis [ISO, ISS]
- interleukin-2 production [ISO, ISS]
- lipid localization [ISO, ISS]
- mitochondrial ATP synthesis coupled proton transport [ISO, ISS]
- mitochondrial calcium ion transport [ISO, ISS]
- mitochondrial protein processing [ISO, ISS]
- mitochondrion localization [ISO]
- mitochondrion organization [ISO, ISS]
- positive regulation of cardiolipin metabolic process [ISO, ISS]
- positive regulation of mitochondrial DNA replication [ISO, ISS]
- positive regulation of mitochondrial membrane potential [ISO, ISS]
- protein oligomerization [ISO, ISS]
- stress-induced mitochondrial fusion [ISO, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- COP9 signalosome [ISO]
- T cell receptor complex [ISO, ISS]
- actin cytoskeleton [ISO, ISS]
- cell [ISO]
- extrinsic component of plasma membrane [ISO, ISS]
- immunological synapse [ISO, ISS]
- intracellular [ISO]
- membrane raft [ISO, ISS]
- mitochondrial inner membrane [ISO, ISS]
- mitochondrial intermembrane space [ISO, ISS]
- mitochondrion [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID