BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PURB
pur-beta
purine rich element binding protein B
GO Process (3)
GO Function (12)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function- RNA binding [ISO]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- SMAD binding [ISO]
- double-stranded DNA binding [ISO]
- mRNA binding [ISO, ISS]
- poly(A) RNA binding [ISO]
- purine-rich negative regulatory element binding [IDA]
- sequence-specific DNA binding transcription factor activity [ISO]
- single-stranded DNA binding [IDA, ISO, ISS]
- transcription factor binding [ISO, ISS]
- translation repressor activity, nucleic acid binding [IDA]
- RNA binding [ISO]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- SMAD binding [ISO]
- double-stranded DNA binding [ISO]
- mRNA binding [ISO, ISS]
- poly(A) RNA binding [ISO]
- purine-rich negative regulatory element binding [IDA]
- sequence-specific DNA binding transcription factor activity [ISO]
- single-stranded DNA binding [IDA, ISO, ISS]
- transcription factor binding [ISO, ISS]
- translation repressor activity, nucleic acid binding [IDA]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID