BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
VAMP3
vesicle-associated membrane protein 3
GO Process (15)
GO Function (4)
GO Component (15)
Gene Ontology Biological Process
- Golgi to plasma membrane protein transport [ISO]
- SNARE complex assembly [ISO]
- calcium ion-dependent exocytosis [ISO]
- exocytosis [IBA]
- mucus secretion [ISO]
- negative regulation of secretion by cell [ISO]
- neurotransmitter secretion [IBA]
- positive regulation of immunoglobulin secretion [ISO]
- positive regulation of receptor recycling [ISO, ISS]
- protein complex assembly [IDA]
- regulation of histamine secretion by mast cell [ISO]
- retrograde transport, endosome to Golgi [ISO, ISS]
- substrate adhesion-dependent cell spreading [ISO, ISS]
- vesicle fusion [IBA]
- vesicle-mediated transport [ISO, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- SNARE complex [IDA, ISO]
- apical plasma membrane [IDA]
- cell [ISO]
- cell surface [ISO]
- clathrin-coated vesicle [ISO]
- clathrin-coated vesicle membrane [IDA]
- cytoplasmic vesicle [ISO]
- cytosol [ISO]
- intracellular [ISO]
- intracellular membrane-bounded organelle [IDA, ISO]
- intracellular organelle [IDA]
- plasma membrane [IDA, ISO, ISS]
- recycling endosome [IDA, ISO]
- secretory granule [ISO]
- synaptic vesicle [IBA]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID