BAIT
ITM2B
Bri, imBRI2
integral membrane protein 2B
GO Process (2)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
VIM
vimentin
GO Process (21)
GO Function (12)
GO Component (16)
Gene Ontology Biological Process
- Bergmann glial cell differentiation [ISO]
- SMAD protein signal transduction [ISO]
- aging [IEP]
- astrocyte development [ISO]
- cellular response to fibroblast growth factor stimulus [IEP]
- decidualization [IEP]
- fat cell differentiation [IEP]
- intermediate filament organization [ISO]
- intermediate filament-based process [ISO]
- lens fiber cell development [ISO]
- negative regulation of neuron projection development [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of glial cell proliferation [IMP]
- regulation of Schwann cell migration [IDA]
- regulation of axonogenesis [IDA]
- response to estradiol [IEP]
- response to radiation [IEP]
- response to selenium ion [IEP]
- response to vitamin D [IEP]
- response to zinc ion [IEP]
- skeletal muscle tissue regeneration [IEP]
Gene Ontology Molecular Function- double-stranded RNA binding [ISO]
- glycoprotein binding [ISO]
- identical protein binding [ISO]
- kinase binding [IPI]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- protein phosphatase 2A binding [IDA]
- scaffold protein binding [ISO]
- structural constituent of cytoskeleton [ISO, ISS]
- structural constituent of eye lens [ISO]
- structural molecule activity [ISO, TAS]
- double-stranded RNA binding [ISO]
- glycoprotein binding [ISO]
- identical protein binding [ISO]
- kinase binding [IPI]
- protein C-terminus binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- protein phosphatase 2A binding [IDA]
- scaffold protein binding [ISO]
- structural constituent of cytoskeleton [ISO, ISS]
- structural constituent of eye lens [ISO]
- structural molecule activity [ISO, TAS]
Gene Ontology Cellular Component
- axon [IDA]
- cell body [IDA]
- cell leading edge [ISO]
- cell projection [IDA, ISO]
- cytoplasm [IDA, ISO, ISS]
- cytoskeleton [IDA, ISO]
- cytosol [IDA, ISO]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- intermediate filament [ISO, ISS]
- intermediate filament cytoskeleton [ISO]
- neuron projection [ISO]
- perinuclear region of cytoplasm [IDA]
- peroxisome [ISO]
- plasma membrane [ISO]
- type III intermediate filament [TAS]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and characterization of the BRI2 interactome in the brain.
BRI family proteins are ubiquitous type II transmembrane proteins but BRI2 is highly expressed in some neuronal tissues. Possible BRI2 functions include neuronal maturation and differentiation. Protein complexes appear to be important in mediating its functions. Previously described BRI2 interactors include the Alzheimer's amyloid precursor protein and protein phosphatase 1, but clearly the identification of novel interactors provides an important ... [more]
Sci Rep Feb. 23, 2018; 8(1);3548 [Pubmed: 29476059]
Throughput
- High Throughput
Curated By
- BioGRID