Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

NDRG1 interacts with APO A-I and A-II and is a functional candidate for the HDL-C QTL on 8q24.

Hunter M, Angelicheva D, Tournev I, Ingley E, Chan DC, Watts GF, Kremensky I, Kalaydjieva L

Hereditary Motor and Sensory Neuropathy Lom (HMSNL) is a severe autosomal recessive peripheral neuropathy, the most common form of demyelinating Charcot-Marie-Tooth (CMT) disease in the Roma (Gypsy) population. The mutated gene, N-myc downstream-regulated gene 1 (NDRG1), is widely expressed and has been implicated in a range of processes and pathways. To gain an insight into NDRG1 function we performed yeast ... [more]

Biochem. Biophys. Res. Commun. Jul. 15, 2005; 332(4);982-92 [Pubmed: 15922294]

Throughput

Low Throughput

Curated By

BioGRID

Interaction Summary

NDRG1

Gene Ontology Biological Process

Gene Ontology Molecular Function

Rab GTPase binding [IDA]cadherin binding [IDA]gamma-tubulin binding [IDA]microtubule binding [IDA]protein binding [IPI]

Gene Ontology Cellular Component

ARL6IP1