BAIT

PRKCZ

PKC-ZETA, PKC2, RP11-181G12.1
protein kinase C, zeta
Alzheimer's Disease Project
Glioblastoma Project
Homo sapiens
PREY

TUBB6

HsT1601, TUBB-5
tubulin, beta 6 class V
GO Process (3)
GO Function (0)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Profiling the interactome of protein kinase C ζ by proteomics and bioinformatics.

Hou C, Li Y, Liu H, Dang M, Qin G, Zhang N, Chen R

Protein kinase C ζ (PKCζ), an isoform of the atypical protein kinase C, is a pivotal regulator in cancer. However, the molecular and cellular mechanisms whereby PKCζ regulates tumorigenesis and metastasis are still not fully understood. In this study, proteomics and bioinformatics analyses were performed to establish a protein-protein interaction (PPI) network associated with PKCζ, laying a stepping stone to ... [more]

Proteome Sci Mar. 02, 2018; 16();5 [Pubmed: 29491746]

Throughput

  • High Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
PRKCZ TUBB6
Affinity Capture-MS
Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

High-BioGRID
-

Curated By

  • BioGRID