BAIT
BAG5
1600025G07Rik, 4930405J06Rik
BCL2-associated athanogene 5
GO Process (7)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [ISO]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [ISO]
- negative regulation of protein refolding [ISO, ISS]
- negative regulation of protein ubiquitination [ISO, ISS]
- negative regulation of ubiquitin-protein transferase activity [ISO, ISS]
- neuron death [ISO, ISS]
- regulation of inclusion body assembly [ISO, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
GAK
D130045N16Rik
cyclin G associated kinase
GO Process (10)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- Golgi organization [IMP]
- cell development [IMP]
- clathrin coat disassembly [IGI]
- clathrin-mediated endocytosis [IMP]
- endoplasmic reticulum organization [IMP]
- epidermal cell differentiation [IMP]
- establishment of skin barrier [IMP]
- forebrain morphogenesis [IMP]
- intrahepatic bile duct development [IMP]
- positive regulation of neural precursor cell proliferation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease.
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause inherited Parkinson disease (PD), and common variants around LRRK2 are a risk factor for sporadic PD. Using protein-protein interaction arrays, we identified BCL2-associated athanogene 5, Rab7L1 (RAB7, member RAS oncogene family-like 1), and Cyclin-G-associated kinase as binding partners of LRRK2. The latter two genes are candidate genes for risk for sporadic PD ... [more]
Proc. Natl. Acad. Sci. U.S.A. Feb. 18, 2014; 111(7);2626-31 [Pubmed: 24510904]
Throughput
- Low Throughput
Curated By
- BioGRID