BAIT

ATP23

YNR020C
Putative metalloprotease of the mitochondrial inner membrane; required for processing of Atp6p; has an additional role in assembly of the F0 sector of the F1F0 ATP synthase complex; substrate of the Mia40p-Erv1p disulfide relay system, and folding is assisted by Mia40p
Saccharomyces cerevisiae (S288c)
PREY

YMR31

mitochondrial 37S ribosomal protein YMR31, L000002726, YFR049W
Mitochondrial ribosomal protein of the small subunit; has similarity to human mitochondrial ribosomal protein MRP-S36
GO Process (1)
GO Function (1)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Saccharomyces cerevisiae (S288c)

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

INA complex liaises the F1Fo-ATP synthase membrane motor modules.

Naumenko N, Morgenstern M, Rucktaeschel R, Warscheid B, Rehling P

The F1F0-ATP synthase translates a proton flux across the inner mitochondrial membrane into a mechanical rotation, driving anhydride bond formation in the catalytic portion. The complex's membrane-embedded motor forms a proteinaceous channel at the interface between Atp9 ring and Atp6. To prevent unrestricted proton flow dissipating the H+-gradient, channel formation is a critical and tightly controlled step during ATP synthase ... [more]

Nat Commun Dec. 01, 2016; 8(1);1237 [Pubmed: 29093463]

Throughput

  • High Throughput

Curated By

  • BioGRID