KRR1
Gene Ontology Biological Process
Gene Ontology Cellular Component
RRP6
Gene Ontology Biological Process
- U1 snRNA 3'-end processing [IGI, IMP]
- U4 snRNA 3'-end processing [IGI, IMP]
- U5 snRNA 3'-end processing [IGI, IMP]
- exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) [IMP]
- histone mRNA catabolic process [IMP]
- nuclear polyadenylation-dependent CUT catabolic process [IGI, IMP]
- nuclear polyadenylation-dependent antisense transcript catabolic process [IMP]
- nuclear polyadenylation-dependent mRNA catabolic process [IMP]
- nuclear polyadenylation-dependent rRNA catabolic process [IGI, IMP]
- nuclear polyadenylation-dependent snRNA catabolic process [IMP]
- nuclear polyadenylation-dependent snoRNA catabolic process [IMP]
- nuclear polyadenylation-dependent tRNA catabolic process [IDA, IGI]
- nuclear retention of pre-mRNA at the site of transcription [IGI]
- nuclear retention of pre-mRNA with aberrant 3'-ends at the site of transcription [IGI]
- polyadenylation-dependent snoRNA 3'-end processing [IMP]
- posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery [IMP]
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Interdependent action of KH domain proteins Krr1 and Dim2 drive the 40S platform assembly.
Ribosome biogenesis begins in the nucleolus with the formation of 90S pre-ribosomes, from which pre-40S and pre-60S particles arise that subsequently follow separate maturation pathways. Here, we show how structurally related assembly factors, the KH domain proteins Krr1 and Dim2, participate in ribosome assembly. Initially, Dim2 (Pno1) orchestrates an early step in small subunit biogenesis through its binding to a ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| RRP6 KRR1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - | |
| KRR1 RRP6 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 2 | BioGRID | 3596234 | |
| KRR1 RRP6 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1217 | BioGRID | 1963425 |
Curated By
- BioGRID