Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Chaperone activity of human small heat shock protein-GST fusion proteins.

Arbach H, Butler C, McMenimen KA

Small heat shock proteins (sHsps) are a ubiquitous part of the machinery that maintains cellular protein homeostasis by acting as molecular chaperones. sHsps bind to and prevent the aggregation of partially folded substrate proteins in an ATP-independent manner. sHsps are dynamic, forming an ensemble of structures from dimers to large oligomers through concentration-dependent equilibrium dissociation. Based on structural studies and ... [more]

Cell Stress Chaperones Dec. 01, 2016; 22(4);503-515 [Pubmed: 28130664]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
CRYAB MDH2
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Low-BioGRID
-

Curated By

  • BioGRID