CACNA1C
Gene Ontology Biological Process
- adult walking behavior [IGI]
- calcium ion import [IBA, ISO]
- calcium ion transmembrane transport [IMP]
- calcium ion transport [IDA, IMP, ISO]
- calcium ion-dependent exocytosis [IMP]
- cellular calcium ion homeostasis [IMP]
- glucose homeostasis [IMP]
- growth hormone secretion [IDA]
- insulin secretion [IMP]
- membrane depolarization during action potential [IBA]
- positive regulation of cytosolic calcium ion concentration [ISO]
- regulation of blood pressure [IMP]
- regulation of ion transmembrane transport [IMP]
- regulation of organ growth [IMP]
- regulation of vasoconstriction [IMP]
- smooth muscle contraction [IMP]
- smooth muscle contraction involved in micturition [IMP]
- synaptic transmission [IMP]
- visual learning [IMP]
Gene Ontology Molecular Function- alpha-actinin binding [ISO]
- calmodulin binding [ISO]
- enzyme binding [IPI]
- high voltage-gated calcium channel activity [IBA, ISO]
- ion channel binding [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein phosphatase 2A binding [ISO]
- voltage-gated calcium channel activity [IDA, IMP, ISO, TAS]
- alpha-actinin binding [ISO]
- calmodulin binding [ISO]
- enzyme binding [IPI]
- high voltage-gated calcium channel activity [IBA, ISO]
- ion channel binding [ISO]
- protein binding [IPI]
- protein domain specific binding [ISO]
- protein phosphatase 2A binding [ISO]
- voltage-gated calcium channel activity [IDA, IMP, ISO, TAS]
Gene Ontology Cellular Component
- T-tubule [IDA, ISO, TAS]
- Z disc [IDA, ISO]
- caveolar macromolecular signaling complex [IDA]
- cell [IMP]
- cytoplasm [ISO]
- cytosol [ISO]
- dendrite [ISO]
- dendritic shaft [IDA]
- integral component of membrane [ISO]
- membrane [IDA, ISO]
- neuronal cell body [IDA, ISO]
- plasma membrane [IDA, ISO]
- postsynaptic density [ISO]
- protein complex [ISO]
- sarcolemma [ISO]
- voltage-gated calcium channel complex [ISO, TAS]
MAP1LC3B
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Autophagy exacerbates electrical remodeling in atrial fibrillation by ubiquitin-dependent degradation of L-type calcium channel.
Autophagy, a bidirectional degradative process extensively occurring in eukaryotes, has been revealed as a potential therapeutic target for several cardiovascular diseases. However, its role in atrial fibrillation (AF) remains largely unknown. This study aimed to determine the role of autophagy in atrial electrical remodeling under AF condition. Here, we reported that autophagic flux was markedly activated in atria of persistent ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID