SHK1
Gene Ontology Biological Process
- Cdc42 protein signal transduction [IGI]
- cellular protein localization [IMP]
- establishment or maintenance of actin cytoskeleton polarity [TAS]
- establishment or maintenance of bipolar cell polarity regulating cell shape [IMP]
- positive regulation of establishment of bipolar cell polarity regulating cell shape [IGI]
- regulation of microtubule cytoskeleton organization [IGI]
- regulation of mitotic cytokinesis [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ORB6
Gene Ontology Biological Process
- cellular response to osmotic stress [IMP]
- cortical actin cytoskeleton stabilization [IMP]
- establishment or maintenance of actin cytoskeleton polarity [IMP]
- establishment or maintenance of bipolar cell polarity regulating cell shape [IMP]
- fungal-type cell wall assembly [IMP]
- maintenance of protein location in cell cortex of cell tip [IMP]
- microtubule cytoskeleton organization [IMP]
- positive regulation of bipolar cell growth [IMP]
- regulation of G2/M transition of mitotic cell cycle [IGI]
- regulation of establishment or maintenance of bipolar cell polarity regulating cell shape [IGI, IMP]
- signal transduction [NAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle.
To identify new genes involved in the control of cell morphogenesis in the fission yeast Schizosaccharomyces pombe we have visually screened for temperature-sensitive mutants that show defects in cell morphology. We have isolated and characterized 64 mutants defining 19 independent genes, 10 of which have not been previously described. One class of mutants, defining 12 orb genes, become round and ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SHK1 ORB6 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 246410 |