CDC2
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [IMP]
- cellular response to nitrogen starvation [IMP]
- negative regulation of G0 to G1 transition [IMP]
- negative regulation of attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation [IMP]
- negative regulation of induction of conjugation with cellular fusion [EXP]
- positive regulation of G1/S transition of mitotic cell cycle [IMP]
- positive regulation of G2/M transition of mitotic cell cycle [IMP]
- positive regulation of mitotic cytokinesis [IMP]
- positive regulation of septation initiation signaling [IMP]
- regulation of cell size [NAS]
- regulation of meiotic cell cycle [IMP]
- response to intra-S DNA damage checkpoint signaling [IMP]
- traversing start control point of mitotic cell cycle [NAS]
Gene Ontology Molecular Function
CDR2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Synthetic Growth Defect
A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell.
Publication
Schizosaccharomyces pombe mutants affected in their division response to starvation.
Schizosaccharomyces pombe mutants have been selected on the basis of an altered response to nutritional stimulation of cell division (changed division response, cdr). Two new loci (cdr1 and cdr2) were identified and characterized. When suspended in nitrogen-free medium wild-type cells underwent stimulated rates of division and became reduced to approximately 30% in protein content with a concomitant 3.6-fold increase in ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CDR2 CDC2 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 246362 | |
| CDR2 CDC2 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 247617 |