ZBTB7B
Gene Ontology Biological Process
- positive regulation of gene expression [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of CD4-positive, alpha-beta T cell differentiation [IMP]
- regulation of CD8-positive, alpha-beta T cell differentiation [IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
Gene Ontology Cellular Component
- nucleoplasm [ISO]
- nucleus [ISO]
DDX3X
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- DNA duplex unwinding [ISO]
- RNA secondary structure unwinding [ISO]
- cellular response to arsenic-containing substance [ISO]
- cellular response to osmotic stress [ISO]
- chromosome segregation [ISO]
- extrinsic apoptotic signaling pathway via death domain receptors [ISO]
- innate immune response [ISO]
- intracellular signal transduction [ISO]
- intrinsic apoptotic signaling pathway [ISO]
- mature ribosome assembly [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of cell growth [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of intrinsic apoptotic signaling pathway [ISO]
- negative regulation of protein complex assembly [ISO]
- negative regulation of translation [ISO]
- positive regulation of G1/S transition of mitotic cell cycle [ISO]
- positive regulation of apoptotic process [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of translation [ISO]
- positive regulation of translational initiation [ISO]
- positive regulation of viral genome replication [ISO]
- response to virus [ISO]
- stress granule assembly [ISO]
Gene Ontology Molecular Function- ATP-dependent DNA helicase activity [ISO]
- ATP-dependent RNA helicase activity [ISO]
- ATPase activity [ISO]
- DNA binding [ISO]
- RNA binding [ISO]
- RNA stem-loop binding [ISO]
- eukaryotic initiation factor 4E binding [ISO]
- mRNA 5'-UTR binding [ISO]
- poly(A) RNA binding [ISO]
- poly(A) binding [ISO]
- protein binding [IPI]
- ribosomal small subunit binding [ISO]
- transcription factor binding [ISO]
- translation initiation factor binding [ISO]
- ATP-dependent DNA helicase activity [ISO]
- ATP-dependent RNA helicase activity [ISO]
- ATPase activity [ISO]
- DNA binding [ISO]
- RNA binding [ISO]
- RNA stem-loop binding [ISO]
- eukaryotic initiation factor 4E binding [ISO]
- mRNA 5'-UTR binding [ISO]
- poly(A) RNA binding [ISO]
- poly(A) binding [ISO]
- protein binding [IPI]
- ribosomal small subunit binding [ISO]
- transcription factor binding [ISO]
- translation initiation factor binding [ISO]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis.
Brown and beige adipocytes convert chemical energy into heat through uncoupled respiration to defend against cold stress. Beyond thermogenesis, brown and beige fats engage other metabolic tissues via secreted factors to influence systemic energy metabolism. How the protein and long noncoding RNA (lncRNA) regulatory networks act in concert to regulate key aspects of thermogenic adipocyte biology remains largely unknown. Here ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ZBTB7B DDX3X | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID