BAIT
ZBTB7B
Thpok, Zfp67, c-Krox
zinc finger and BTB domain containing 7B
GO Process (5)
GO Function (6)
GO Component (2)
Gene Ontology Biological Process
- positive regulation of gene expression [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- regulation of CD4-positive, alpha-beta T cell differentiation [IMP]
- regulation of CD8-positive, alpha-beta T cell differentiation [IMP]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
- DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- protein binding [IPI]
- protein homodimerization activity [IDA]
- sequence-specific DNA binding transcription factor activity [IDA]
Gene Ontology Cellular Component
- nucleoplasm [ISO]
- nucleus [ISO]
Mus musculus
PREY
HNRNPM
2610023M21Rik, AA409009, Hnrpm, mKIAA4193, RP24-225N8.1
heterogeneous nuclear ribonucleoprotein M
GO Process (1)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis.
Brown and beige adipocytes convert chemical energy into heat through uncoupled respiration to defend against cold stress. Beyond thermogenesis, brown and beige fats engage other metabolic tissues via secreted factors to influence systemic energy metabolism. How the protein and long noncoding RNA (lncRNA) regulatory networks act in concert to regulate key aspects of thermogenic adipocyte biology remains largely unknown. Here ... [more]
Proc. Natl. Acad. Sci. U.S.A. Dec. 22, 2016; 114(34);E7111-E7120 [Pubmed: 28784777]
Throughput
- High Throughput
Curated By
- BioGRID