BAIT
TNPO2
IPO3, KPNB2B, TRN2
transportin 2
GO Process (0)
GO Function (2)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
PREY
RPL4
L4
ribosomal protein L4
GO Process (13)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
Molecular basis for protection of ribosomal protein L4 from cellular degradation.
Eukaryotic ribosome biogenesis requires the nuclear import of ∼80 nascent ribosomal proteins and the elimination of excess amounts by the cellular degradation machinery. Assembly chaperones recognize nascent unassembled ribosomal proteins and transport them together with karyopherins to their nuclear destination. We report the crystal structure of ribosomal protein L4 (RpL4) bound to its dedicated assembly chaperone of L4 (Acl4), revealing ... [more]
Nat Commun Dec. 02, 2016; 8();14354 [Pubmed: 28148929]
Throughput
- Low Throughput
Curated By
- BioGRID