BAIT
HSPH1
HSP105, HSP105A, HSP105B, NY-CO-25, RP11-173P16.1
heat shock 105kDa/110kDa protein 1
GO Process (3)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ADD1
AI256389
adducin 1 (alpha)
GO Process (14)
GO Function (8)
GO Component (14)
Gene Ontology Biological Process
- actin filament bundle assembly [ISO]
- barbed-end actin filament capping [ISO]
- cell morphogenesis [IMP]
- cell volume homeostasis [IMP]
- cellular response to retinoic acid [ISO]
- erythrocyte differentiation [IMP]
- hemoglobin metabolic process [IMP]
- homeostasis of number of cells within a tissue [IMP]
- in utero embryonic development [IMP]
- multicellular organism growth [IMP]
- negative regulation of actin filament polymerization [ISO]
- positive regulation of angiogenesis [ISO]
- positive regulation of endocytosis [ISO]
- positive regulation of protein binding [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- F-actin capping protein complex [ISO]
- cell [IMP]
- cytoskeleton [IDA]
- dendrite [ISO]
- dendritic spine [ISO]
- focal adhesion [ISO]
- intermediate filament cytoskeleton [ISO]
- membrane [IDA]
- nucleoplasm [ISO]
- nucleus [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- postsynaptic density [ISO]
- synapse [ISO]
Mus musculus
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Screening of Hsp105alpha-binding proteins using yeast and bacterial two-hybrid systems.
Hsp105alpha is a 105-kDa stress protein, which is expressed constitutively at especially high levels in the brain compared with other tissues in mammals, and is also induced by a variety of stressors. Recently, we have shown that Hsp105alpha binds to alpha-tubulin and prevents the heat-induced disaggregation of microtubules. To further elucidate the function of Hsp105alpha, we searched for Hsp105alpha-binding proteins ... [more]
Biochem. Biophys. Res. Commun. Feb. 06, 2004; 314(2);396-402 [Pubmed: 14733918]
Throughput
- Low Throughput
Curated By
- BioGRID