BAIT
PTPRR
Gmcp1, PTP-SL, PTPBR7, RPTPRR, mPTP213
protein tyrosine phosphatase, receptor type, R
GO Process (5)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CAMK2A
CaMKII, R74975, mKIAA0968
calcium/calmodulin-dependent protein kinase II alpha
GO Process (13)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- calcium ion transport [IMP]
- ionotropic glutamate receptor signaling pathway [ISO]
- peptidyl-serine phosphorylation [IMP, ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of calcium ion transport [IMP]
- positive regulation of cardiac muscle cell apoptotic process [IMP]
- protein autophosphorylation [IMP, ISO]
- protein phosphorylation [IDA, ISO]
- regulation of mitochondrial membrane permeability involved in apoptotic process [IMP]
- regulation of neuronal synaptic plasticity [IMP]
- regulation of neurotransmitter secretion [IMP]
- response to ischemia [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
PTPBR7 binding proteins in myelinating neurons of the mouse brain.
Mouse protein tyrosine phosphatase PTPBR7 is a receptor-like, transmembrane protein that is localized on the surface of neuronal cells. Its protein phosphatase activity is reduced upon multimerization, and PTPBR7-deficient mice display motor coordination defects. Extracellular molecules that may influence PTPBR7 activity, however, remain to be determined. We here show that the PTPBR7 extracellular domain binds to highly myelinated regions in ... [more]
Int. J. Biol. Sci. Aug. 19, 2011; 7(7);978-91 [Pubmed: 21850207]
Throughput
- Low Throughput
Curated By
- BioGRID