BAIT
PTPRR
Gmcp1, PTP-SL, PTPBR7, RPTPRR, mPTP213
protein tyrosine phosphatase, receptor type, R
GO Process (5)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CAMK2B
RP23-340E18.5
calcium/calmodulin-dependent protein kinase II, beta
GO Process (17)
GO Function (5)
GO Component (3)
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- activation of meiosis involved in egg activation [IMP]
- calcium ion transport [IMP]
- cell projection morphogenesis [ISO]
- inhibitory G-protein coupled receptor phosphorylation [IDA]
- long-term synaptic potentiation [ISO]
- neuromuscular process controlling balance [IMP]
- peptidyl-serine phosphorylation [IDA]
- positive regulation of apoptotic signaling pathway [IDA]
- positive regulation of dendritic spine morphogenesis [ISO]
- positive regulation of neuron projection development [ISO]
- positive regulation of phospholipase A2 activity [ISO]
- positive regulation of synapse maturation [ISO]
- protein autophosphorylation [IMP, ISO]
- regulation of long-term neuronal synaptic plasticity [IMP]
- regulation of synaptic transmission, cholinergic [IMP]
- response to cadmium ion [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
PTPBR7 binding proteins in myelinating neurons of the mouse brain.
Mouse protein tyrosine phosphatase PTPBR7 is a receptor-like, transmembrane protein that is localized on the surface of neuronal cells. Its protein phosphatase activity is reduced upon multimerization, and PTPBR7-deficient mice display motor coordination defects. Extracellular molecules that may influence PTPBR7 activity, however, remain to be determined. We here show that the PTPBR7 extracellular domain binds to highly myelinated regions in ... [more]
Int. J. Biol. Sci. Aug. 19, 2011; 7(7);978-91 [Pubmed: 21850207]
Throughput
- Low Throughput
Curated By
- BioGRID