CNTNAP1
Gene Ontology Biological Process
- axon cargo transport [ISO, ISS]
- cytoskeleton organization [ISO, ISS]
- myelination [TAS]
- neuromuscular process controlling balance [ISO, ISS]
- neuromuscular process controlling posture [ISO, ISS]
- neuron projection development [ISO]
- neuron projection morphogenesis [ISO, ISS]
- neuronal action potential propagation [ISO, ISS]
- paranodal junction assembly [ISO, ISS, TAS]
- protein localization to paranode region of axon [ISO, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CNTN1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Identification of a novel contactin-associated transmembrane receptor with multiple domains implicated in protein-protein interactions.
Receptor protein tyrosine phosphatase beta (RPTPbeta) expressed on the surface of glial cells binds to the glycosylphosphatidylinositol (GPI)-anchored recognition molecule contactin on neuronal cells leading to neurite outgrowth. We describe the cloning of a novel contactin-associated transmembrane receptor (p190/Caspr) containing a mosaic of domains implicated in protein-protein interactions. The extracellular domain of Caspr contains a neurophilin/coagulation factor homology domain, a ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID