PIP5KL1
PIP5K1C
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- adherens junction assembly [TAS]
- axon guidance [TAS]
- clathrin-mediated endocytosis [TAS]
- neutrophil chemotaxis [TAS]
- phagocytosis [TAS]
- phosphatidylinositol biosynthetic process [TAS]
- phospholipid metabolic process [TAS]
- single organismal cell-cell adhesion [TAS]
- small molecule metabolic process [TAS]
- synaptic vesicle endocytosis [TAS]
- synaptic vesicle exocytosis [TAS]
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Identification and characterization of a phosphoinositide phosphate kinase homolog.
Phosphatidylinositol 4,5-bisphosphate (PI(4,5)P(2)) plays a central role in regulating the actin cytoskeleton as a substrate for phosphoinositide 3-kinase and phospholipase C as well as by binding directly to proteins that control the processes of actin monomer sequestration, filament severing, capping, nucleation, cross-linking, and bundling (Ma, L., Cantley, L. C., Janmey, P. A., and Kirschner, M. W. (1998) J. Cell Biol. ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID