PREY
ACLY
ACL, ATPCL, CLATP
ATP citrate lyase
GO Process (10)
GO Function (2)
GO Component (7)
Gene Ontology Biological Process
- ATP catabolic process [TAS]
- cellular lipid metabolic process [TAS]
- citrate metabolic process [TAS]
- coenzyme A metabolic process [TAS]
- energy reserve metabolic process [TAS]
- lipid biosynthetic process [IDA]
- long-chain fatty-acyl-CoA biosynthetic process [TAS]
- positive regulation of cellular metabolic process [TAS]
- small molecule metabolic process [TAS]
- triglyceride biosynthetic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.
Lamins are key nuclear proteins which are important for maintaining nuclear structure and function. Mutations in lamins cause a spectrum of genetic diseases termed as laminopathies. RING finger containing E3 ubiquitin ligase, RNF123, is transcriptionally upregulated in cells expressing rod domain lamin A mutations. However, the functional relevance of RNF123 in laminopathic cells is not clear. Using a mass spectrometry-based ... [more]
FEBS J. Jun. 01, 2018; 285(12);2243-2262 [Pubmed: 29676528]
Throughput
- High Throughput
Curated By
- BioGRID