BAIT

SLC30A3

ZNT3
solute carrier family 30 (zinc transporter), member 3
Homo sapiens
PREY

AP3B1

ADTB3, ADTB3A, HPS, HPS2, PE
adaptor-related protein complex 3, beta 1 subunit
GO Process (4)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation.

Salazar G, Love R, Werner E, Doucette MM, Cheng S, Levey A, Faundez V

Synaptic vesicles (SV) are generated by two different mechanisms, one AP-2 dependent and one AP-3 dependent. It has been uncertain, however, whether these mechanisms generate SV that differ in molecular composition. We explored this hypothesis by analyzing the targeting of ZnT3 and synaptophysin both to PC12 synaptic-like microvesicles (SLMV) as well as SV isolated from wild-type and AP-3-deficient mocha brains. ... [more]

Mol. Biol. Cell Feb. 01, 2004; 15(2);575-87 [Pubmed: 14657250]

Throughput

  • Low Throughput

Curated By

  • BioGRID