BAIT

GLE1

GLE1L, LCCS, LCCS1, hGLE1
GLE1 RNA export mediator
GO Process (1)
GO Function (2)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

The mRNA export factor human Gle1 interacts with the nuclear pore complex protein Nup155.

Rayala HJ, Kendirgi F, Barry DM, Majerus PW, Wente SR

The protein Gle1 is required for export of mRNAs from the nucleus to the cytoplasm in both lower and higher eukaryotic cells. In human (h) cells, shuttling of hGle1 between the nucleus and cytoplasm is essential for bulk mRNA export. To date, no hGle1-interacting proteins have been reported and the mechanism by which hGle1 interacts with the nuclear pore complex ... [more]

Mol. Cell Proteomics Feb. 01, 2004; 3(2);145-55 [Pubmed: 14645504]

Throughput

  • Low Throughput

Curated By

  • BioGRID