BAIT
CTDSPL2
HSPC129, HSPC058
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
EPPK1
EPIPL, EPIPL1
epiplakin 1
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
A systematic study of nuclear interactome of C-terminal domain small phosphatase-like 2 using inducible expression system and shotgun proteomics.
RNA polymerase II C-terminal domain phosphatases are newly emerging family of phosphatases that contain FCPH domain with Mg+2-binding DXDX(T/V) signature motif. Its subfamily includes small CTD phosphatases (SCPs). Recently, we identified several interacting partners of human SCP1 with appearance of dephosphorylation and O-GlcNAcylation. In this study, using an established cell line with inducible CTDSPL2 protein (a member of the new ... [more]
BMB Rep Jun. 01, 2016; 49(6);319-24 [Pubmed: 26674342]
Throughput
- High Throughput
Curated By
- BioGRID