BAIT

CTDSPL2

HSPC129, HSPC058
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY

HNRNPM

CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1, hnRNP M
heterogeneous nuclear ribonucleoprotein M
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

A systematic study of nuclear interactome of C-terminal domain small phosphatase-like 2 using inducible expression system and shotgun proteomics.

Kang N, Koo J, Wang S, Hur SJ, Bahk YY

RNA polymerase II C-terminal domain phosphatases are newly emerging family of phosphatases that contain FCPH domain with Mg＋2-binding DXDX(T/V) signature motif. Its subfamily includes small CTD phosphatases (SCPs). Recently, we identified several interacting partners of human SCP1 with appearance of dephosphorylation and O-GlcNAcylation. In this study, using an established cell line with inducible CTDSPL2 protein (a member of the new ... [more]

BMB Rep Jun. 01, 2016; 49(6);319-24 [Pubmed: 26674342]

Throughput

  • High Throughput

Curated By

  • BioGRID