BAIT
WWOX
D16S432E, FOR, FRA16D, HHCMA56, PRO0128, SCAR12, SDR41C1, WOX1
WW domain containing oxidoreductase
GO Process (7)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- cellular response to transforming growth factor beta stimulus [IDA]
- negative regulation of Wnt signaling pathway [IDA]
- oxidation-reduction process [TAS]
- positive regulation of extrinsic apoptotic signaling pathway [ISS]
- positive regulation of transcription from RNA polymerase II promoter [ISS]
- skeletal system morphogenesis [ISS]
- steroid metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
ESYT2
CHR2SYT, E-Syt2, FAM62B, tcag7.562
extended synaptotagmin-like protein 2
GO Process (0)
GO Function (7)
GO Component (5)
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Delineating WWOX Protein Interactome by Tandem Affinity Purification-Mass Spectrometry: Identification of Top Interactors and Key Metabolic Pathways Involved.
It has become clear from multiple studies that WWOX (WW domain-containing oxidoreductase) operates as a "non-classical" tumor suppressor of significant relevance in cancer progression. Additionally, WWOX has been recognized for its role in a much wider array of human pathologies including metabolic conditions and central nervous system related syndromes. A myriad of putative functional roles has been attributed to WWOX ... [more]
Front Oncol Jan. 09, 2019; 8();591 [Pubmed: 30619736]
Throughput
- High Throughput
Curated By
- BioGRID