BAIT
TXNDC17
TRP14, TXNL5
thioredoxin domain containing 17
GO Process (2)
GO Function (4)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CFL1
CFL, HEL-S-15
cofilin 1 (non-muscle)
GO Process (13)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
- Fc-gamma receptor signaling pathway involved in phagocytosis [TAS]
- Rho protein signal transduction [TAS]
- actin cytoskeleton organization [TAS]
- axon guidance [TAS]
- blood coagulation [TAS]
- cytoskeleton organization [IMP]
- innate immune response [TAS]
- negative regulation of apoptotic process [TAS]
- platelet activation [TAS]
- platelet degranulation [TAS]
- regulation of cell morphogenesis [IMP]
- regulation of dendritic spine morphogenesis [IMP]
- response to virus [IEP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-alpha signaling pathways.
The possible roles of a 14-kDa human thioredoxin (Trx)-related protein (TRP14) in TNF-alpha signaling were studied in comparison with those of Trx1 by RNA interference in HeLa cells. Depletion of TRP14 augmented the TNF-alpha-induced phosphorylation and degradation of I kappa B alpha as well as the consequent activation of NF-kappa B to a greater extent than did Trx1 depletion. Deficiency ... [more]
J. Biol. Chem. Jan. 30, 2004; 279(5);3151-9 [Pubmed: 14607843]
Throughput
- Low Throughput
Curated By
- BioGRID