YWHAQ
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
FXYD1
Gene Ontology Biological Process
- chloride transmembrane transport [TAS]
- chloride transport [TAS]
- ion transmembrane transport [TAS]
- muscle contraction [TAS]
- positive regulation of sodium ion export from cell [ISS]
- regulation of cardiac muscle cell membrane potential [ISS]
- regulation of heart contraction [TAS]
- regulation of sodium ion transmembrane transporter activity [ISS]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Reconstituted Complex
An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.
Publication
Ischemia-induced phosphorylation of phospholemman directly activates rat cardiac Na/K-ATPase.
Regulation of the Na/K ATPase by protein kinases is model-specific. We have observed a profound activation of the sarcolemmal Na/K ATPase during cardiac ischemia, which is masked by an inhibitor of the enzyme in the cytosol. The aim of these studies was to characterize the pathways involved in this activation in the Langendorff-perfused rat heart. Na/K ATPase activity was determined ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID