BAIT
NR1I3
CAR, CAR1, MB67
nuclear receptor subfamily 1, group I, member 3
GO Process (6)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function- DNA binding [TAS]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- androgen receptor activity [TAS]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [TAS]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription coactivator activity [TAS]
- DNA binding [TAS]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- androgen receptor activity [TAS]
- ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity [TAS]
- sequence-specific DNA binding transcription factor activity [TAS]
- transcription coactivator activity [TAS]
Homo sapiens
PREY
HSPA4
APG-2, HEL-S-5a, HS24/P52, HSPH2, RY, hsp70, hsp70RY
heat shock 70kDa protein 4
GO Process (3)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Tripartite Motif Containing 24 Acts as a Novel Coactivator of the Constitutive Active/Androstane Receptor.
The constitutive androstane receptor (CAR) is a nuclear receptor that acts as a transcription factor for a variety of genes, including genes encoding xenobiotic, steroid, and drug-metabolizing enzymes and transporters. Transactivation of a target gene by a transcription factor is generally mediated through the concerted and stepwise recruitment of various proteins termed coregulators, including coactivators and corepressors. In this study, ... [more]
Drug Metab. Dispos. Dec. 01, 2017; 46(1);46-52 [Pubmed: 29101097]
Throughput
- High Throughput
Curated By
- BioGRID