BAIT
MARK4
MARK4L, MARK4S, MARKL1, MARKL1L, PAR-1D
MAP/microtubule affinity-regulating kinase 4
GO Process (5)
GO Function (7)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
TUBA1A
B-ALPHA-1, LIS3, TUBA3
tubulin, alpha 1a
GO Process (8)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
MARK4 is a novel microtubule-associated proteins/microtubule affinity-regulating kinase that binds to the cellular microtubule network and to centrosomes.
The MARK protein kinases were originally identified by their ability to phosphorylate a serine motif in the microtubule-binding domain of tau that is critical for microtubule binding. Here, we report the cloning and expression of a novel human paralog, MARK4, which shares 75% overall homology with MARK1-3 and is predominantly expressed in brain. Homology is most pronounced in the catalytic ... [more]
J. Biol. Chem. Feb. 13, 2004; 279(7);5915-23 [Pubmed: 14594945]
Throughput
- Low Throughput
Curated By
- BioGRID