DST
Gene Ontology Biological Process
- cell motility [IMP]
- cytoskeleton organization [IMP]
- extracellular matrix organization [TAS]
- hemidesmosome assembly [IDA]
- integrin-mediated signaling pathway [NAS]
- intermediate filament cytoskeleton organization [IEP, ISS, NAS]
- maintenance of cell polarity [IMP]
- microtubule cytoskeleton organization [IDA]
- response to wounding [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Z disc [IDA]
- actin cytoskeleton [IDA]
- axon [IDA]
- basal plasma membrane [NAS]
- basement membrane [TAS]
- cell leading edge [IDA]
- cytoplasm [IDA, ISS]
- cytoplasmic membrane-bounded vesicle [IDA]
- cytosol [TAS]
- extracellular vesicular exosome [IDA]
- focal adhesion [IDA]
- hemidesmosome [IDA, TAS]
- intermediate filament cytoskeleton [IDA]
- microtubule cytoskeleton [IDA]
- microtubule plus-end [IDA]
- nucleus [IDA]
DCTN1
Gene Ontology Biological Process
- G2/M transition of mitotic cell cycle [TAS]
- activation of signaling protein activity involved in unfolded protein response [TAS]
- antigen processing and presentation of exogenous peptide antigen via MHC class II [TAS]
- cellular protein metabolic process [TAS]
- endoplasmic reticulum unfolded protein response [TAS]
- mitotic cell cycle [TAS]
- mitotic nuclear division [NAS]
- nervous system development [NAS]
- retrograde transport, endosome to Golgi [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
BPAG1n4 is essential for retrograde axonal transport in sensory neurons.
Disruption of the BPAG1 (bullous pemphigoid antigen 1) gene results in progressive deterioration in motor function and devastating sensory neurodegeneration in the null mice. We have previously demonstrated that BPAG1n1 and BPAG1n3 play important roles in organizing cytoskeletal networks in vivo. Here, we characterize functions of a novel BPAG1 neuronal isoform, BPAG1n4. Results obtained from yeast two-hybrid screening, blot overlay ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| DCTN1 DST | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID