BAIT

ZBTB38

CIBZ, PPP1R171, ZNF921
zinc finger and BTB domain containing 38
UPS Project
Homo sapiens
PREY

BAG2

BAG-2, dJ417I1.2, RP3-496N17.2
BCL2-associated athanogene 2
Alzheimer's Disease Project
GO Process (2)
GO Function (2)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Stabilization of the methyl-CpG binding protein ZBTB38 by the deubiquitinase USP9X limits the occurrence and toxicity of oxidative stress in human cells.

Miotto B, Marchal C, Adelmant G, Guinot N, Xie P, Marto JA, Zhang L, Defossez PA

Reactive oxygen species (ROS) are a byproduct of cell metabolism, and can also arise from environmental sources, such as toxins or radiation. Depending on dose and context, ROS have both beneficial and deleterious roles in mammalian development and disease, therefore it is crucial to understand how these molecules are generated, sensed, and detoxified. The question of how oxidative stress connects ... [more]

Nucleic Acids Res. May. 18, 2018; 46(9);4392-4404 [Pubmed: 29490077]

Throughput

  • High Throughput

Curated By

  • BioGRID