BAIT
GABARAP
ATG8A, GABARAP-a, MM46, HT004
GABA(A) receptor-associated protein
GO Process (7)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
BIRC6
APOLLON, BRUCE
baculoviral IAP repeat containing 6
GO Process (7)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
The IAP family member BRUCE regulates autophagosome-lysosome fusion.
Autophagy has an important role in cellular homeostasis by degrading and recycling cytotoxic components. Ubiquitination is known to target cargoes for autophagy; however, key components of this pathway remain elusive. Here we performed an RNAi screen to uncover ubiquitin modifiers that are required for starvation-induced macroautophagy in mammalian cells. Our screen uncovered BRUCE/Apollon/Birc6, an IAP protein, as a new autophagy ... [more]
Nat Commun Dec. 09, 2017; 9(1);599 [Pubmed: 29426817]
Throughput
- Low Throughput
Curated By
- BioGRID