SERPING1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SELE
Gene Ontology Biological Process
- actin filament-based process [IDA]
- activation of phospholipase C activity [IMP]
- blood coagulation [TAS]
- calcium-mediated signaling [TAS]
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [IMP]
- inflammatory response [TAS]
- leukocyte cell-cell adhesion [IDA]
- leukocyte migration [TAS]
- leukocyte migration involved in inflammatory response [TAS]
- leukocyte tethering or rolling [IMP]
- positive regulation of receptor internalization [IDA]
- regulation of inflammatory response [TAS]
- response to interleukin-1 [IDA]
- response to lipopolysaccharide [TAS]
- response to tumor necrosis factor [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Complement regulatory protein C1 inhibitor binds to selectins and interferes with endothelial-leukocyte adhesion.
C1 inhibitor (C1INH), a member of the serine proteinase inhibitor (serpin) family, is an inhibitor of proteases in the complement system, the contact system of kinin generation, and the intrinsic coagulation pathway. It is the most heavily glycosylated plasma protein, containing 13 definitively identified glycosylation sites as well as an additional 7 potential glycosylation sites. C1INH consists of two distinct ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID