PPP1R9B
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- actin filament organization [IPI]
- calcium-mediated signaling [IMP]
- cell migration [ISO]
- cellular response to morphine [IMP]
- dendrite development [IMP]
- filopodium assembly [ISO]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [IMP]
- regulation of protein phosphorylation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ADD1
Gene Ontology Biological Process
- actin filament bundle assembly [ISO]
- barbed-end actin filament capping [ISO]
- cell morphogenesis [IMP]
- cell volume homeostasis [IMP]
- cellular response to retinoic acid [ISO]
- erythrocyte differentiation [IMP]
- hemoglobin metabolic process [IMP]
- homeostasis of number of cells within a tissue [IMP]
- in utero embryonic development [IMP]
- multicellular organism growth [IMP]
- negative regulation of actin filament polymerization [ISO]
- positive regulation of angiogenesis [ISO]
- positive regulation of endocytosis [ISO]
- positive regulation of protein binding [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- F-actin capping protein complex [ISO]
- cell [IMP]
- cytoskeleton [IDA]
- dendrite [ISO]
- dendritic spine [ISO]
- focal adhesion [ISO]
- intermediate filament cytoskeleton [ISO]
- membrane [IDA]
- nucleoplasm [ISO]
- nucleus [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- postsynaptic density [ISO]
- synapse [ISO]
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.
Glutamatergic projections from the cortex and dopaminergic projections from the substantia nigra or ventral tegmental area synapse on dendritic spines of specific GABAergic medium spiny neurons (MSNs) in the striatum. Direct pathway MSNs (dMSNs) are positively coupled to protein kinase A (PKA) signaling and activation of these neurons enhance specific motor programs whereas indirect pathway MSNs (iMSNs) are negatively coupled ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
PPP1R9B ADD1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - |
Curated By
- BioGRID