PPP1R9B
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- actin filament organization [IPI]
- calcium-mediated signaling [IMP]
- cell migration [ISO]
- cellular response to morphine [IMP]
- dendrite development [IMP]
- filopodium assembly [ISO]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [IMP]
- regulation of protein phosphorylation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CAMK2A
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- calcium ion transport [IMP]
- ionotropic glutamate receptor signaling pathway [ISO]
- peptidyl-serine phosphorylation [IMP, ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of calcium ion transport [IMP]
- positive regulation of cardiac muscle cell apoptotic process [IMP]
- protein autophosphorylation [IMP, ISO]
- protein phosphorylation [IDA, ISO]
- regulation of mitochondrial membrane permeability involved in apoptotic process [IMP]
- regulation of neuronal synaptic plasticity [IMP]
- regulation of neurotransmitter secretion [IMP]
- response to ischemia [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.
Glutamatergic projections from the cortex and dopaminergic projections from the substantia nigra or ventral tegmental area synapse on dendritic spines of specific GABAergic medium spiny neurons (MSNs) in the striatum. Direct pathway MSNs (dMSNs) are positively coupled to protein kinase A (PKA) signaling and activation of these neurons enhance specific motor programs whereas indirect pathway MSNs (iMSNs) are negatively coupled ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
PPP1R9B CAMK2A | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - | |
PPP1R9B CAMK2A | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 0.4012 | BioGRID | 3499331 | |
PPP1R9B CAMK2A | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID