PPP1R9B
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- actin filament organization [IPI]
- calcium-mediated signaling [IMP]
- cell migration [ISO]
- cellular response to morphine [IMP]
- dendrite development [IMP]
- filopodium assembly [ISO]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [IMP]
- regulation of protein phosphorylation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CAMK2B
Gene Ontology Biological Process
- G1/S transition of mitotic cell cycle [IMP]
- activation of meiosis involved in egg activation [IMP]
- calcium ion transport [IMP]
- cell projection morphogenesis [ISO]
- inhibitory G-protein coupled receptor phosphorylation [IDA]
- long-term synaptic potentiation [ISO]
- neuromuscular process controlling balance [IMP]
- peptidyl-serine phosphorylation [IDA]
- positive regulation of apoptotic signaling pathway [IDA]
- positive regulation of dendritic spine morphogenesis [ISO]
- positive regulation of neuron projection development [ISO]
- positive regulation of phospholipase A2 activity [ISO]
- positive regulation of synapse maturation [ISO]
- protein autophosphorylation [IMP, ISO]
- regulation of long-term neuronal synaptic plasticity [IMP]
- regulation of synaptic transmission, cholinergic [IMP]
- response to cadmium ion [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.
Glutamatergic projections from the cortex and dopaminergic projections from the substantia nigra or ventral tegmental area synapse on dendritic spines of specific GABAergic medium spiny neurons (MSNs) in the striatum. Direct pathway MSNs (dMSNs) are positively coupled to protein kinase A (PKA) signaling and activation of these neurons enhance specific motor programs whereas indirect pathway MSNs (iMSNs) are negatively coupled ... [more]
Throughput
- High Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| PPP1R9B CAMK2B | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - | |
| PPP1R9B CAMK2B | Proximity Label-MS Proximity Label-MS An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods. | High | 0.4098 | BioGRID | 3499332 | |
| PPP1R9B CAMK2B | Reconstituted Complex Reconstituted Complex An interaction is detected between purified proteins in vitro. | Low | - | BioGRID | - |
Curated By
- BioGRID