BAIT
PPP1R9B
SPL, Spn, RP23-112C19.3
protein phosphatase 1, regulatory subunit 9B
GO Process (10)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- actin filament organization [IPI]
- calcium-mediated signaling [IMP]
- cell migration [ISO]
- cellular response to morphine [IMP]
- dendrite development [IMP]
- filopodium assembly [ISO]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [IMP]
- regulation of protein phosphorylation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CAR2
AI131712, CAII, Ca2, Car-2, Ltw-5, Lvtw-5
carbonic anhydrase 2
GO Process (13)
GO Function (2)
GO Component (11)
Gene Ontology Biological Process
- angiotensin-activated signaling pathway [ISO]
- carbon dioxide transport [IC, IMP]
- morphogenesis of an epithelium [IMP]
- positive regulation of bone resorption [ISO]
- positive regulation of cellular pH reduction [IMP, ISO]
- positive regulation of dipeptide transmembrane transport [IMP]
- positive regulation of osteoclast differentiation [ISO]
- positive regulation of synaptic transmission, GABAergic [IGI]
- regulation of anion transport [ISO]
- regulation of chloride transport [IMP]
- regulation of intracellular pH [IMP]
- regulation of pH [IC]
- secretion [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.
Glutamatergic projections from the cortex and dopaminergic projections from the substantia nigra or ventral tegmental area synapse on dendritic spines of specific GABAergic medium spiny neurons (MSNs) in the striatum. Direct pathway MSNs (dMSNs) are positively coupled to protein kinase A (PKA) signaling and activation of these neurons enhance specific motor programs whereas indirect pathway MSNs (iMSNs) are negatively coupled ... [more]
Proteomes Dec. 17, 2018; 6(4); [Pubmed: 30562941]
Throughput
- High Throughput
Curated By
- BioGRID