BAIT
PPP1R9B
SPL, Spn, RP23-112C19.3
protein phosphatase 1, regulatory subunit 9B
GO Process (10)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- actin filament organization [IPI]
- calcium-mediated signaling [IMP]
- cell migration [ISO]
- cellular response to morphine [IMP]
- dendrite development [IMP]
- filopodium assembly [ISO]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [IMP]
- regulation of protein phosphorylation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CDC42
AI747189, AU018915, RP23-246F18.2
cell division cycle 42
GO Process (50)
GO Function (6)
GO Component (12)
Gene Ontology Biological Process
- GTP catabolic process [ISA]
- Golgi organization [ISO]
- Rho protein signal transduction [TAS]
- actin filament branching [ISO]
- actin filament bundle assembly [IMP]
- actin filament organization [ISO]
- adherens junction organization [IMP]
- canonical Wnt signaling pathway [IMP]
- cardiac conduction system development [IGI]
- cellular protein localization [IMP]
- dendritic cell migration [IGI]
- endosomal transport [TAS]
- epidermis morphogenesis [IMP]
- epithelial cell-cell adhesion [IMP]
- epithelial-mesenchymal cell signaling [IMP]
- establishment of Golgi localization [ISO]
- establishment or maintenance of apical/basal cell polarity [IMP]
- establishment or maintenance of cell polarity [TAS]
- filopodium assembly [IDA]
- hair follicle morphogenesis [IMP]
- hair follicle placode formation [IMP]
- heart contraction [IGI]
- keratinization [IMP]
- keratinocyte development [IMP]
- multicellular organism growth [IMP]
- negative regulation of gene expression [IMP]
- neuron fate determination [IMP]
- nuclear migration [IMP]
- nucleus localization [IMP]
- organelle transport along microtubule [ISO]
- positive regulation of DNA replication [ISO]
- positive regulation of JNK cascade [ISO]
- positive regulation of MAPK cascade [IDA]
- positive regulation of gene expression [IMP]
- positive regulation of hair follicle cell proliferation [IMP]
- positive regulation of intracellular protein transport [ISO]
- positive regulation of metalloenzyme activity [ISO]
- positive regulation of neuron apoptotic process [ISO]
- positive regulation of peptidyl-serine phosphorylation [IMP]
- positive regulation of phosphatidylinositol 3-kinase activity [IMP]
- positive regulation of protein phosphorylation [IMP]
- positive regulation of synapse structural plasticity [ISO]
- regulation of mitosis [IMP]
- regulation of protein catabolic process [IMP]
- regulation of protein heterodimerization activity [IDA]
- regulation of protein kinase activity [IMP]
- regulation of protein metabolic process [IMP]
- regulation of protein stability [IMP]
- single organismal cell-cell adhesion [IMP, TAS]
- sprouting angiogenesis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.
Glutamatergic projections from the cortex and dopaminergic projections from the substantia nigra or ventral tegmental area synapse on dendritic spines of specific GABAergic medium spiny neurons (MSNs) in the striatum. Direct pathway MSNs (dMSNs) are positively coupled to protein kinase A (PKA) signaling and activation of these neurons enhance specific motor programs whereas indirect pathway MSNs (iMSNs) are negatively coupled ... [more]
Proteomes Dec. 17, 2018; 6(4); [Pubmed: 30562941]
Throughput
- High Throughput
Curated By
- BioGRID