PPP1R9B
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- actin filament organization [IPI]
- calcium-mediated signaling [IMP]
- cell migration [ISO]
- cellular response to morphine [IMP]
- dendrite development [IMP]
- filopodium assembly [ISO]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [IMP]
- regulation of protein phosphorylation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GRIN1
Gene Ontology Biological Process
- adult locomotory behavior [IMP]
- associative learning [IMP]
- calcium ion homeostasis [IDA]
- calcium ion transmembrane transport [IGI, ISO]
- calcium ion transport [IDA, IMP]
- cation transport [IGI, ISO]
- cellular calcium ion homeostasis [IMP]
- cerebral cortex development [IMP]
- conditioned taste aversion [IMP]
- ion transmembrane transport [IMP]
- ionotropic glutamate receptor signaling pathway [IDA, IGI, ISO]
- learning [IMP]
- learning or memory [IMP]
- long-term memory [IMP]
- male mating behavior [IMP]
- memory [IMP]
- negative regulation of neuron apoptotic process [IGI, IMP]
- neuromuscular process [IMP]
- olfactory learning [IMP]
- pons maturation [IMP]
- positive regulation of apoptotic process [IGI]
- positive regulation of cell death [ISO]
- positive regulation of excitatory postsynaptic membrane potential [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- prepulse inhibition [IMP]
- propylene metabolic process [IDA]
- protein tetramerization [ISO]
- regulation of axonogenesis [IMP]
- regulation of cell communication [IMP]
- regulation of dendrite morphogenesis [IMP]
- regulation of excitatory postsynaptic membrane potential [IGI, IMP]
- regulation of ion transmembrane transport [ISO]
- regulation of long-term neuronal synaptic plasticity [IMP]
- regulation of membrane potential [IDA, IMP, ISO]
- regulation of neuron apoptotic process [IGI, IMP]
- regulation of neuronal synaptic plasticity [IMP]
- regulation of respiratory gaseous exchange [IMP]
- regulation of synapse assembly [IMP]
- regulation of synaptic plasticity [IMP]
- respiratory gaseous exchange [IMP]
- response to amphetamine [IGI, IMP]
- response to ethanol [ISO]
- response to morphine [IMP]
- rhythmic process [ISO]
- sensory perception of pain [IMP]
- social behavior [IMP]
- startle response [IMP]
- suckling behavior [IMP]
- synaptic transmission [TAS]
- synaptic transmission, glutamatergic [IMP]
- visual learning [IGI, IMP]
Gene Ontology Molecular Function- N-methyl-D-aspartate selective glutamate receptor activity [IDA, IGI, IMP, ISO]
- calcium channel activity [IDA, IGI, ISO]
- calcium ion binding [IDA]
- calmodulin binding [IDA]
- cation channel activity [IGI]
- enzyme binding [ISO]
- extracellular-glutamate-gated ion channel activity [IBA]
- glutamate binding [ISO]
- glutamate receptor binding [ISO]
- glycine binding [IMP, ISO]
- ionotropic glutamate receptor activity [ISO]
- neurotransmitter binding [ISO]
- protein binding [IPI]
- protein dimerization activity [ISO]
- protein heterodimerization activity [ISO]
- receptor binding [IPI, ISO]
- voltage-gated cation channel activity [ISO]
- N-methyl-D-aspartate selective glutamate receptor activity [IDA, IGI, IMP, ISO]
- calcium channel activity [IDA, IGI, ISO]
- calcium ion binding [IDA]
- calmodulin binding [IDA]
- cation channel activity [IGI]
- enzyme binding [ISO]
- extracellular-glutamate-gated ion channel activity [IBA]
- glutamate binding [ISO]
- glutamate receptor binding [ISO]
- glycine binding [IMP, ISO]
- ionotropic glutamate receptor activity [ISO]
- neurotransmitter binding [ISO]
- protein binding [IPI]
- protein dimerization activity [ISO]
- protein heterodimerization activity [ISO]
- receptor binding [IPI, ISO]
- voltage-gated cation channel activity [ISO]
Gene Ontology Cellular Component
- N-methyl-D-aspartate selective glutamate receptor complex [IPI, ISO]
- cell [IMP]
- cell surface [IDA]
- cytoplasm [IDA]
- dendrite [IDA, ISO]
- dendrite membrane [ISO]
- dendritic spine [IDA, ISO]
- endoplasmic reticulum [IDA]
- excitatory synapse [ISO]
- growth cone [NAS]
- integral component of plasma membrane [ISO]
- membrane [IC, IDA]
- neuronal postsynaptic density [IDA]
- postsynaptic density [IDA, ISO]
- postsynaptic membrane [IDA]
- synapse [IDA, ISO]
- synaptic cleft [ISO]
- synaptic vesicle [IDA]
- terminal bouton [ISO]
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.
Glutamatergic projections from the cortex and dopaminergic projections from the substantia nigra or ventral tegmental area synapse on dendritic spines of specific GABAergic medium spiny neurons (MSNs) in the striatum. Direct pathway MSNs (dMSNs) are positively coupled to protein kinase A (PKA) signaling and activation of these neurons enhance specific motor programs whereas indirect pathway MSNs (iMSNs) are negatively coupled ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
PPP1R9B GRIN1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | Low | - | BioGRID | - |
Curated By
- BioGRID