BAIT
PPP1R9B
SPL, Spn, RP23-112C19.3
protein phosphatase 1, regulatory subunit 9B
GO Process (10)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
- actin cytoskeleton organization [TAS]
- actin filament organization [IPI]
- calcium-mediated signaling [IMP]
- cell migration [ISO]
- cellular response to morphine [IMP]
- dendrite development [IMP]
- filopodium assembly [ISO]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [IMP]
- regulation of protein phosphorylation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PLCB1
3110043I21Rik, AI132408, Plcb, mKIAA0581, RP23-418D21.3
phospholipase C, beta 1
GO Process (36)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
- G-protein coupled acetylcholine receptor signaling pathway [IMP]
- G2/M transition of mitotic cell cycle [IDA, NAS]
- activation of meiosis involved in egg activation [IDA]
- brain development [NAS]
- cell adhesion [IC]
- cerebral cortex development [IMP]
- erythrocyte differentiation [TAS]
- fat cell differentiation [IDA]
- glutamate receptor signaling pathway [IMP]
- insulin receptor signaling pathway [TAS]
- insulin-like growth factor receptor signaling pathway [IDA]
- interleukin-1-mediated signaling pathway [ISO]
- interleukin-12-mediated signaling pathway [ISO]
- interleukin-15-mediated signaling pathway [ISO]
- mRNA processing [TAS]
- macrophage differentiation [NAS]
- memory [IMP]
- negative regulation of monocyte extravasation [IDA]
- negative regulation of transcription, DNA-templated [IDA]
- oocyte maturation [NAS]
- positive regulation of CD24 biosynthetic process [IDA]
- positive regulation of G1/S transition of mitotic cell cycle [IDA]
- positive regulation of GTPase activity [ISO]
- positive regulation of JNK cascade [ISO]
- positive regulation of acrosome reaction [IMP]
- positive regulation of developmental growth [IMP]
- positive regulation of embryonic development [IMP]
- positive regulation of interleukin-12 production [IMP]
- positive regulation of myoblast differentiation [IDA]
- positive regulation of sodium:proton antiporter activity [NAS]
- positive regulation of transcription, DNA-templated [IDA]
- regulation of G-protein coupled receptor protein signaling pathway [IMP]
- regulation of fertilization [IMP]
- response to monosaccharide [ISO]
- response to peptide hormone [ISO]
- signal transduction [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Proteomic Analysis of the Spinophilin Interactome in Rodent Striatum Following Psychostimulant Sensitization.
Glutamatergic projections from the cortex and dopaminergic projections from the substantia nigra or ventral tegmental area synapse on dendritic spines of specific GABAergic medium spiny neurons (MSNs) in the striatum. Direct pathway MSNs (dMSNs) are positively coupled to protein kinase A (PKA) signaling and activation of these neurons enhance specific motor programs whereas indirect pathway MSNs (iMSNs) are negatively coupled ... [more]
Proteomes Dec. 17, 2018; 6(4); [Pubmed: 30562941]
Throughput
- High Throughput
Curated By
- BioGRID